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Jeremy Koemel discusses detecting low-intensity PFAS features when MS/MS signal is too weak, and how they work around it.

As metabolomics datasets balloon, Siuzdak explains using retention time and in-source fragmentation checks to separate real molecules from artifacts.

Liquid chromatography-mass spectrometry (LC-MS) profiling links blood biomarkers to cardiotoxicity.

Masashi Serizawa and Andrea Gargano, researchers at the Van ‘t Hoff Institute for Molecular Sciences (HIMS, University of Amsterdam) sit down with LCGC International to discuss how reversed-phase liquid chromatography and high-resolution mass spectrometry (RPLC-HRMS) analysis of degraded PLGA oligomers reveals block-length differences behind solubility variation in copolymers.

Sheher Mohsin explains how CCS measurements add a physical confirmation layer beyond mass and retention time in PFAS analysis.

Siuzdak separates true standard-based empirical spectra from artifactual signals, warning AI trained on flawed data risks perpetuating errors.

High-performance liquid chromatography (HPLC) profiles serum N-glycan ratios to track psoriasis severity and treatment.

This week, Chromatography Online presented ASMS 2026 recaps, HILIC deep-dives, AI in drug discovery, and a public health story from GC-MS.

Gas chromatography-mass spectroscopy (GC–MS) and high-performance liquid chromatography (HPLC) reveal how stir-frying builds complex flavors stage by stage.

In the final installment of this four-part series, Yifan Liu of Northeastern University (Boston, MA) forecasts where metabolomics will be headed in the next ten years.

James Grinias from Rowan University, New Jersey, USA, discusses sustainability and modern capillary LC systems.

Two-dimensional gas chromatography (2D- GC) identifies 88 sulfur compounds shaping the key aromas of soy sauce flavor Baijiu.

The panel unpacks the defining challenge of PFAS analysis: a chemical class so vast and diverse it pushes current methods to their limits.